It’s called supercompensation, and it’s why your muscles grow from training.īasically, we can’t have anabolism without catabolism.īut when you start taking ingredients that keep pinging that AMPK enzyme, you will keep suppressing the anabolic pathway. Our AMPK pathway triggers naturally but when we lift weights, the catabolism is more than matched by the anabolic response that follows.
Now that’s all fine and dandy in the normal metabolic cycle of your body. However, while it doesn’t directly break down muscle protein – and hence muscle – it can inhibit its growth. The AMPK enzyme, on the other hand, is catabolic. If they are central enough, like AMPK, insulin, mTOR and noradrenaline (norepinephrine) they can induce a cascade of reactions which add up to have major effects.įor example, mTOR (mammalian target of rapamycin) lights up the anabolic pathway for increased muscle growth, and thus any compound that activates it (e.g. There’s a downside to AMPK activation? How could this be?Įnzymes, hormones and catecholamines can have some heavy influence on the body’s metabolic balance. What they won’t tell you in the marketing hype is the downside of activating the enzyme. And yes, it should increase energy when and if AMPK is activated. It’s definitely a good thing as far as fat reduction goes. Rather than say it “tells your body to stop storing fat and start converting it to energy”, which is how the diet pill industry will phrase it (and LCR health do), it’s more a case of triggering an increased turnover of available fuel, be it fat or carbs. It also increases the uptake of both fats and carbs from the blood into cells. It also handles some other enzymes that help towards this goal. This enzyme is responsible for breaking things down, like fat and glycogen/carbohydrate and oxidizing (burning) them. I thought getting fatter by the day would help me live until I’m 200 years old, just like John Candy and Elvis did.ĪMPK is an enzyme – stands for Adenosine Monophosphate Activated Protein Kinase. I’m so relieved we rolled out the Harvard Medical School card on that one. The company that makes Active PK – LCR Health (Live Cell Research) – go on to cite Harvard Medical School, saying a slimmer waistline is “one of the most effective paths to a longer life”. So, the inclusions in this bottle of pills are supposed to light up the AMPK enzyme, which does a bunch of fancy things that ultimately lead to: It’s kind of a non-committal way of saying “life extension” but rather than the absolute promise of adding years to your life, it’s more like adding life to your years. There are a bunch of ingredients, compounds and enzymes that have been shown to enhance longevity, but what is it? The bottle’s label calls it a “Longevity Activator”, which is probably as close to “Immortality Potion” as the FDA agent allowed them to get, in between his or her bouts of hysterical laughter down the phone. But I’ll get to that.įirst let’s look at what it is supposed to do for you. Oh, and sure, “it can work for anybody”……except loads of people. The company’s response starts with this: “One of the amazing things about it is it can work for anybody…” “How do I know if I’m a good candidate?” – apparently that’s one of the FAQs the company gets asked all…the…time. Throw in the odd “only natural ingredients” and “caffeine free” and people will be willing to part with wads of cash for the opportunity to try it. It’s got a kind of clinical, pharmaceutical vibe, and the marketing blurb jacks your mind-brain up on science-waffle about AMPK. Hey, perhaps you could sell some Active PK while you’re there. Unfortunately, 3 bottles of the stuff won’t bestow you with everlasting life, but it’s a great topic of conversation when you’re in the hospital waiting room getting ready for a colonoscopy or something. If you want to burn excess body fat and reduce your daily caloric intake then click here to view our highest rated recommended diet product Active PK contains an ingredient nicknamed “the immortality herb”. That aside, LCR Health are a reputable company with a good reputation within the industry, Some of the customer feedback we have seen is not inspiring. They have the Gynostemma dosage spot on.īut it’s hard to envisage what their customer base could be or should be. Active PK looks like a specialist product – and to some degree it is.